2C-B was first synthesized and described in the 1970s by Alexander Shulgin, an American chemist and pharmacologist. Shulgin developed 2C-B as part of a series of psychoactive substances. 

The company “Drittewelle” in Leipzig then sold the substance for some time under the brand names NEXUS® (10 mg capsules) and EROX® (5 mg tablets) in order to treat impotence and as an aphrodisiac. In the 1980s, 2C-B gained popularity in the techno and rave scene and was often used as a party drug. 

In 1993, 2C-B was added to the Narcotics law and in the late 1990s and was classified as illegal by many countries. [2]

In General, many say the effects of 2C-B are “in between” LSD and MDMA but to be honest, the impact of 2C-B in the body is not fully understood until now. [2]

It is assumed that 2C-B binds as a partial agonist or antagonist to various receptors in the brain, especially to the serotonin receptors 5-HT2A and 5-HT2C. [1]

2C-B is a substance that can be taken either orally or nasally. The dose depends on various factors such as body weight, gender and daily condition of the user. A small dose of 2C-B is sufficient to achieve the desired effects, although the dose required depends on the mode of administration: For oral use, a light dosage of 5-15 mg is recommended, a moderate dosage is between 15-30 mg and a strong dosage between 25-50 mg. For nasal consumption, a much lower dose is needed. Rule of thumb: About half the oral dose, to achieve the same effects![3]

The onset concerning the 2C-B effects when consuming it orally occurs after about 20-30 minutes, the maximum effect is reached after about 1.5 hours and the effect lasts for about 4-8 hours. The effect then wears off relatively quickly within about an hour. However, mild after-effects may still be felt over a period of approx. 2-4 hours. [3] When the consumption of 2C-B is performed nasally the effects may already start after 5-10 minutes. However, regarding the maximum effect and the after-effects, the same rules are valid for nasal consumption as for oral consumption. [4]

Psychogenic effects are observed from a dosage of 10mg. It leads to various symptoms starting with Euphoria, increased empathy, and soft visual distortions. With increasing dosage, effects like altered perception of time and space and pseudo hallucinations are perceived. In addition, 2C-B leads to a sympathetic activation which comes across to with an increase in heart rate, blood pressure and body temperature. [2] Insecurity, fear, anxiety, disorientation and confusion may also occur, especially at high doses. [3]

However, we don’t know what long-term effects 2C-B may have on our physical and mental health.

And how do I analyse a sample to see if and how much 2C-B it contains?  

This is already possible with the miraculix MDMA QTest, even for pressed pills. The QTest tells you by the intensity of the coloring how much 2C-B the pill or powder contains. The two additional color reactions give additional security in the detection of mixtures (for example, you can easily detect a mixture with MDMA). We are already in the process of developing a separate quantitative test kit for 2C-B, so stay tuned!